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Vaccines for the control of:
Infectious hematopoietic necrosis virus (IHNV), Project funding: USDA SBIR PhI & II
Infectious salmon anemia virus (ISAV), Project funding: USDA SBIR PhI & II
Viral Nervous Necrosis or Viral encephalopathy and retinopathy (Nodavirus), Project funding: NSF SBIR PhI & II
Listonella anguillarum, Project funding: NOAA SBIR PhI & II
Aeromonas salmonicida, Project funding: NOAA SBIR PhI & II
Infectious Hematopoietic Necrosis Virus (IHNV)
Family: Rhabdoviridae
Genus: Novirhabodivirus
Vaccine type: Inactivated virus
Use: Prevention of IHN disease of salmon and trout
Project Status: Phase II transitioning to Phase III. We have developed and evaluated a dozen different inactivated IHNV vaccine prototypes in our Phase I and II R&D program. The research led to the identification of a highly efficacious vaccine. We are currently transitioning to Phase III commercialization and welcome inquiries regarding field testing the inactivated IHNV vaccine as well as smaller controlled efficacy studies in 2007.
Infectious salmon anemia virus (ISAV)
Family: Orthomyxoviridae
Genus: Isavirus
Vaccine type: Recombinant protein
Use: Prevention of ISA disease of Atlantic salmon
Project Status: Phase II transitioning to Phase III. We have developed and evaluated two dozen different recombinant protein vaccines in our Phase I and II R&D program. The research led to the identification of a number of efficacious recombinant vaccines. We have found that that the formulation as a multi-epitope vaccine increases efficacy. We are currently refining the vaccine and are transitioning the project from Phase II to Phase III commercialization. We welcome inquiries regarding field testing of the recombinant ISAV vaccine as well as smaller controlled efficacy studies during 2007.
Nodavirus
Viral Family: Nodaviridae
Genus: Betanodavirus
Vaccine type: Recombinant protein
Use: Prevention of viral encephalopathy and retinopathy (VER)/viral nervous necrosis (VNN) of Atlantic cod and halibut
Project Status: Phase II. About a half dozen recombinant protein vaccines have been engineered and manufactured. The performance of the vaccine(s) are being evaluated in Atlantic cod. The compatibility of the vaccine with the Aeromonas salmonicida and Listonella anguillarum vaccine is also being evaluated. We welcome enquiries regarding laboratory efficacy testing and experimental use.
Aeromonas salmonicida and Listonella anguillarum
Family: Vibrionaceae
Genus: Aeromonas and Listonella
Vaccine type: Inactivated bacterin
Use: Prevention of disease caused by Aeromonas salmonicida and Listonella anguillarum in Atlantic cod and halibut.
Project status: Phase II. The vaccines have been formulated as mono and bivalent vaccines. The performance of the vaccine(s) are being evaluated in Atlantic cod. The compatibility of the vaccines with the recombinant nodavirus vaccine is also being evaluated. We welcome enquiries regarding laboratory efficacy testing and experimental use.
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